Aging revolves around cellular senescence, a state of cell arrest. Extreme stress levels or cell proliferation can lead to the accumulation of senescent cells, which limits the capacity of tissues to function and regenerate in aged organisms. Nicotinamide phosphoribosyltransferase (Nampt) is a crucial enzyme incorporated in cellular senescence, and it plays a vital role in… Continue reading NAD⁺ Regulating Enzyme Keeps Mouse Cells Replicating Under Stress
Category: Aging & Longevity
Blood Cancer Therapy May Provide a Strategy for Age-Related Disease Treatments
Chimeric antigen receptor (CAR) T cells, genetically altered immune cells extracted from patients and subsequently reintroduced, have obtained notoriety for treating blood malignancies. However, is it possible to utilize these cells to combat conditions like aging? In a study published in the journal Nature, Lowe and colleagues from Sloan Kettering Institute in New York demonstrated… Continue reading Blood Cancer Therapy May Provide a Strategy for Age-Related Disease Treatments
Harvard Researchers Link Death from Sleep Deprivation to the Gut
Key Points About one-third of people don’t attain the Center for Disease Control’s recommended seven hours or more of sleep per night. At the same time, very few of us experience the paranoia and disorientation that goes along with extreme sleep deprivation. In rare circumstances, prolonged sleep loss leads to death, leading researchers to question… Continue reading Harvard Researchers Link Death from Sleep Deprivation to the Gut
Keeping the Mouse Body Clock Young to Counter Aging Requires NAD⁺
Circadian rhythms—physiological changes that follow a daily cycle, like the sleep-wake cycle—get disrupted as we get older, which can contribute to the development of age-related diseases. However, the mechanisms and signals linking circadian rhythms and aging are unclear. A research team from Northwestern University published an article in the journal Molecular Cell showing that the… Continue reading Keeping the Mouse Body Clock Young to Counter Aging Requires NAD⁺