Chilling News for Vascular Aging: Cold Exposure Reduces Blood Vessel Hardening while Deterring Senescence  

Key Points:  Cold exposure refers to when the body is exposed to temperatures below 68 °F (20°C), which is about room temperature. Some cold exposure methods, such as ice baths, are known to reduce inflammation and alleviate muscle soreness, but the effect of cold exposure on aging, particularly vascular aging, is still being explored.  Now,… Continue reading Chilling News for Vascular Aging: Cold Exposure Reduces Blood Vessel Hardening while Deterring Senescence  

Heart Health Improved by Gold Particles That Boost NAD⁺, Study Shows  

Key Points Tiny bits of gold covered with a chemical found in a range of plants, including chamomile, might protect the heart from damage caused by an effective drug for cancer. Gold nanoparticles covered with apigenin—which has several modes of action, including boosting the levels of the indispensable molecule NAD+—prevented heart cell death and the… Continue reading Heart Health Improved by Gold Particles That Boost NAD⁺, Study Shows  

Stem Cell Therapy Improves Heart Function and Reduces Risk of Stroke and Heart Attack: Largest Human Trial of its Kind 

Key Points:  The most common cause of heart failure (HF) — when the heart cannot efficiently pump blood — is a heart attack, which typically occurs in older individuals. Standard drug treatments for HF do not restore heart function but rather keep the heart from pumping too much. However, the latest clinical trial suggests that… Continue reading Stem Cell Therapy Improves Heart Function and Reduces Risk of Stroke and Heart Attack: Largest Human Trial of its Kind 

Canadian Study Suggests NAD⁺ Could Help Prevent Heart Failure 

Key Points:  After the age of 50, the number of individuals affected by heart failure (HF) doubles with each decade. Medications and surgeries help HF patients keep their hearts from working too hard, but there are currently no standard curative interventions for HF. With this in mind, it could be possible to prevent heart failure… Continue reading Canadian Study Suggests NAD⁺ Could Help Prevent Heart Failure 

Study Shows NAD⁺ Protects Heart and Brain From Heart Attack

Key Points: As we age, our bodies are more susceptible to heart attacks and other instances of irregular heart rhythms. Cardiopulmonary resuscitation (CPR) is the standard of care following a heart attack. However, heart attack-induced oxygen deprivation can often lead to long-term cardiovascular and neurological issues that can lead to death. Now, researchers have found… Continue reading Study Shows NAD⁺ Protects Heart and Brain From Heart Attack

Study Shows Potent Antioxidant Reduces Artery Cholesterol Buildup

Key Points: N-acetylcysteine (NAC) has long been used in clinical settings for acetaminophen (Tylenol) overdose. However, research has shown that it may also protect against DNA damage and support a healthy immune system, both of which are important parts of maintaining our health as we age. A more recent study shows that it may also… Continue reading Study Shows Potent Antioxidant Reduces Artery Cholesterol Buildup

Italian Study Shows Senolytics Promote Cardiac Regeneration After Heart Attack

Key Points:  Nearly 80% of all deaths linked to cardiovascular disease are among elderly individuals, as aging seems to be particularly harsh on the heart. Accordingly, advanced age increases the risk of cardiovascular disease — encompassing atherosclerosis, hypertension, and myocardial infarction — which leads to heart failure. In part, this is due to a decline… Continue reading Italian Study Shows Senolytics Promote Cardiac Regeneration After Heart Attack

Scientists Reduce Cardiac Dysfunction in Diabetes by Boosting NAD⁺

Key Points: Diabetic mice display cardiac dysfunction and mitochondrial impairments.   NR supplementation increases cellular NAD+ levels and helps restore mitochondrial function. Restoration of mitochondrial function reduces cellular (oxidative) stress, mediating the repair of cardiac function. Our heart functions to nourish each of our cells, however, its ability to pump nutrients and oxygen can become compromised.… Continue reading Scientists Reduce Cardiac Dysfunction in Diabetes by Boosting NAD⁺

Scientists Recreate Functional Human Heart Tissue from Animal Scaffolding

Key Points: Human cells successfully repopulate a rabbit heart that has been decellularized – cleared of all (rabbit) cells.  When blood is passed through the heart, it visibly pumps. The repopulated heart responds to medications that affect heart rate. Heart attacks can be deadly or cause irreparable damage, especially with advanced age. This is due… Continue reading Scientists Recreate Functional Human Heart Tissue from Animal Scaffolding

Study Shows Traditional Chinese Medicine Delays Cardiac Aging

Key Points:  Treatment with THBru improves heart function, reduces fibrosis (scarring), and decreases senescent (aged) cells in a mouse model for aging.  THBru delays cardiac aging by activating mitophagy – the clearance of defective/dead mitochondria.  Removing damaged cellular components, such as defective mitochondria via mitophagy, is vital to thwarting energy depletion, oxidative stress, and inflammation,… Continue reading Study Shows Traditional Chinese Medicine Delays Cardiac Aging