Key Points: As we age, our bodies are more susceptible to heart attacks and other instances of irregular heart rhythms. Cardiopulmonary resuscitation (CPR) is the standard of care following a heart attack. However, heart attack-induced oxygen deprivation can often lead to long-term cardiovascular and neurological issues that can lead to death. Now, researchers have found… Continue reading Study Shows NAD⁺ Protects Heart and Brain From Heart Attack
Category: Cardiovascular
Study Shows Potent Antioxidant Reduces Artery Cholesterol Buildup
Key Points: N-acetylcysteine (NAC) has long been used in clinical settings for acetaminophen (Tylenol) overdose. However, research has shown that it may also protect against DNA damage and support a healthy immune system, both of which are important parts of maintaining our health as we age. A more recent study shows that it may also… Continue reading Study Shows Potent Antioxidant Reduces Artery Cholesterol Buildup
Italian Study Shows Senolytics Promote Cardiac Regeneration After Heart Attack
Key Points: Nearly 80% of all deaths linked to cardiovascular disease are among elderly individuals, as aging seems to be particularly harsh on the heart. Accordingly, advanced age increases the risk of cardiovascular disease — encompassing atherosclerosis, hypertension, and myocardial infarction — which leads to heart failure. In part, this is due to a decline… Continue reading Italian Study Shows Senolytics Promote Cardiac Regeneration After Heart Attack
Scientists Reduce Cardiac Dysfunction in Diabetes by Boosting NAD⁺
Key Points: Diabetic mice display cardiac dysfunction and mitochondrial impairments. NR supplementation increases cellular NAD+ levels and helps restore mitochondrial function. Restoration of mitochondrial function reduces cellular (oxidative) stress, mediating the repair of cardiac function. Our heart functions to nourish each of our cells, however, its ability to pump nutrients and oxygen can become compromised.… Continue reading Scientists Reduce Cardiac Dysfunction in Diabetes by Boosting NAD⁺
Scientists Recreate Functional Human Heart Tissue from Animal Scaffolding
Key Points: Human cells successfully repopulate a rabbit heart that has been decellularized – cleared of all (rabbit) cells. When blood is passed through the heart, it visibly pumps. The repopulated heart responds to medications that affect heart rate. Heart attacks can be deadly or cause irreparable damage, especially with advanced age. This is due… Continue reading Scientists Recreate Functional Human Heart Tissue from Animal Scaffolding
Study Shows Traditional Chinese Medicine Delays Cardiac Aging
Key Points: Treatment with THBru improves heart function, reduces fibrosis (scarring), and decreases senescent (aged) cells in a mouse model for aging. THBru delays cardiac aging by activating mitophagy – the clearance of defective/dead mitochondria. Removing damaged cellular components, such as defective mitochondria via mitophagy, is vital to thwarting energy depletion, oxidative stress, and inflammation,… Continue reading Study Shows Traditional Chinese Medicine Delays Cardiac Aging
Researchers Show Cognitive-Boosting Cocktail Reduces Brain Senescence, Inflammation, and DNA Damage
Key Points: Aging is multifaceted and complex, involving a myriad of interacting biological pathways that gradually collapse and lead to organ and tissue dysfunction. Many of the current anti-aging therapeutics target only one specific biological pathway, narrowing their impact on slowing, preventing, or reversing aging. This is why scientists have turned to drug combinations that… Continue reading Researchers Show Cognitive-Boosting Cocktail Reduces Brain Senescence, Inflammation, and DNA Damage
Large Study Finds Increased Risk of Heart Disease Linked to Napping
Key Points: Individuals who napped for over 30 minutes in the daytime were more likely to succumb to cardiovascular disease, hypertension (high blood pressure), or stroke. Daytime napping for over an hour leads to more profound effects than napping for just 30 minutes. Daytime sleeping (napping) is commonly thought to rejuvenate and promote healthy habits,… Continue reading Large Study Finds Increased Risk of Heart Disease Linked to Napping
New Longevity Molecule Found to Prolong Lifespan and Delay Cardiac and Muscle Aging
Key Points: Our genetic blueprints (DNA) are constantly being studied to identify longevity-linked genes and pathways that may hold the key to prolonging our lifespan. One particular gene that has strong ties to longevity is Cisd2. In addition to extending the lifespan of rodents through increased activity, activation of Cisd2 protects against cardiac dysfunction and… Continue reading New Longevity Molecule Found to Prolong Lifespan and Delay Cardiac and Muscle Aging
Study Finds Berberine Protects Against Cardiac Aging by Regulating Anti-Aging Protein
Key Points: Berberine slows signs of aging in heart cells, including decreasing cellular senescence – a critical state where cells can no longer divide and multiply (proliferate). Many beneficial effects of berberine require klotho, an anti-aging protein associated with extending lifespan and mitigating age-related diseases. Old rats treated with berberine exhibit less cardiac fibrosis –… Continue reading Study Finds Berberine Protects Against Cardiac Aging by Regulating Anti-Aging Protein