Key Points: Age reversal refers to restoring an organism’s youth. This includes prolonging the organism’s lifespan and healthspan — the duration of life lived without disease and age-related deficits. One of the more ambitious goals of aging science is to reverse aging in humans, and a new study suggests we are one step closer to doing just… Continue reading Study Suggests We are Now Closer to Reversing Aging via Gene Therapy
Category: Epigenetics
Study Shows Rapamycin Mimics Dietary Restriction-Induced Brain Aging Reversal
Key Points: Aging leads to changes in gene activation linked to brain function in the hippocampus of mice. Rapamycin restores 69.5% of the same age-associated gene changes as dietary restriction. Dietary restriction restores more age-associated genes than rapamycin. For those of us who wish to live longer, the two most powerful methods for extending lifespan… Continue reading Study Shows Rapamycin Mimics Dietary Restriction-Induced Brain Aging Reversal
Reversing Age-Related Vision Loss with Embryonic Gene Delivery
Several age-related studies seek to understand how gene regulation is affected by methyl groups, which are compounds known to attach to DNA via a process called methylation. Decreases in gene activation are associated with increases in methylation. As humans age, methylation patterns diverge, and cells end up reading incorrect genes, promoting age-related diseases and malfunctional… Continue reading Reversing Age-Related Vision Loss with Embryonic Gene Delivery