Study Suggests We are Now Closer to Reversing Aging via Gene Therapy

Key Points: Age reversal refers to restoring an organism’s youth. This includes prolonging the organism’s lifespan and healthspan — the duration of life lived without disease and age-related deficits. One of the more ambitious goals of aging science is to reverse aging in humans, and a new study suggests we are one step closer to doing just… Continue reading Study Suggests We are Now Closer to Reversing Aging via Gene Therapy

Study Shows Rapamycin Mimics Dietary Restriction-Induced Brain Aging Reversal

Key Points:  Aging leads to changes in gene activation linked to brain function in the hippocampus of mice.  Rapamycin restores 69.5% of the same age-associated gene changes as dietary restriction.   Dietary restriction restores more age-associated genes than rapamycin.  For those of us who wish to live longer, the two most powerful methods for extending lifespan… Continue reading Study Shows Rapamycin Mimics Dietary Restriction-Induced Brain Aging Reversal

Reversing Age-Related Vision Loss with Embryonic Gene Delivery

Several age-related studies seek to understand how gene regulation is affected by methyl groups, which are compounds known to attach to DNA via a process called methylation. Decreases in gene activation are associated with increases in methylation. As humans age, methylation patterns diverge, and cells end up reading incorrect genes, promoting age-related diseases and malfunctional… Continue reading Reversing Age-Related Vision Loss with Embryonic Gene Delivery