A complication that frequently occurs in patients who undergo open cardiovascular repair or open-heart surgery is acute kidney injury, and evidence suggests that this condition is associated with diminished health- and lifespan. Unfortunately, the chances of hospital mortality, accruing health care costs, receiving long-term care, and developing chronic kidney disease are all increased in people… Continue reading Elysium Health™ Announces Phase II Trial for Preventing Acute Kidney Injury Following Heart Surgery with NAD⁺ Plus Antioxidant Supplement
Month: December 2020
Resveratrol Restores Cognition (In Mice with Alzheimer’s)
Over the last few years, overconsumption of calories that derive from saturated fat has been a catalyst to the progression of global obesity, and metabolic and brain disorders have also been linked to caloric overconsumption. Mouse and human models have provided overwhelming evidence that Alzheimer’s disease, along with other manifestations of cognitive impairment, can be… Continue reading Resveratrol Restores Cognition (In Mice with Alzheimer’s)
NAD+ Allays Multiple Sclerosis in Mice
Multiple sclerosis is a seriously disabling disease involving our immune system’s attack on healthy cells. This self-inflicted response progressively causes nervous system inflammation and the stripping of protective fats coating nerve projections (demyelination). Figuring out how to suppress this nervous system inflammation and keep nerves healthy would be an attractive therapeutic strategy. Wang and colleagues… Continue reading NAD+ Allays Multiple Sclerosis in Mice
How Does Space Travel Affect Natural Aging?
Growing older can take a serious toll on the body. Bones become brittle, muscle shrinks, the immune system loses strength, and age-related ailments like arthritis can set in. More serious complications like declining cognitive function and heart disease can also take hold as the later years of life progress. These symptoms can also come from… Continue reading How Does Space Travel Affect Natural Aging?
Reversing Age-Related Vision Loss with Embryonic Gene Delivery
Several age-related studies seek to understand how gene regulation is affected by methyl groups, which are compounds known to attach to DNA via a process called methylation. Decreases in gene activation are associated with increases in methylation. As humans age, methylation patterns diverge, and cells end up reading incorrect genes, promoting age-related diseases and malfunctional… Continue reading Reversing Age-Related Vision Loss with Embryonic Gene Delivery
Challenges to the Validity of Patent for Nicotinamide Riboside Production
The presence of cellular nicotinamide adenine dinucleotide (NAD+), a compound critical for health and longevity, is known to decline as humans age. However, direct consumption of NAD+ lacks efficiency in restoring NAD+ within cells. Instead, a more effective method of boosting NAD+ involves utilizing precursor molecules of NAD+. Thus, there is widespread interest and competition… Continue reading Challenges to the Validity of Patent for Nicotinamide Riboside Production
Drug Rejuvenates Neuron Function and Cognition in Aged Mice
As the global population continues to age and grow in number, age-related cognitive impairment has progressively become a pressing issue. A deleterious neurological mechanism called the integrated stress response (ISR) becomes apparent as humans age and promotes age-associated cognitive impairment. In a study published on December 1st (year) in the open-access journal eLife, Rosi and… Continue reading Drug Rejuvenates Neuron Function and Cognition in Aged Mice
The Science Behind Adele’s Weight Loss
Most of us know that health and longevity go hand in hand with our dietary choices, which has led to many people paying close attention to what they eat. Although reducing calorie intake and fasting are proven weight loss and longevity-promoting methods, they’re not easy or exciting things to do every day. But wouldn’t it… Continue reading The Science Behind Adele’s Weight Loss