Contents Importance of Sleep Stages of Sleep: The Need for Deep and REM Sleep Circadian Rhythm-Aligned Sleep Promotes General Health Good Sleep Counters Death and Disease Lifespan Hormones Cardiovascular System Immune System The Brain, Memory, and Mental Health Optimizing Sleep and Circadian Rhythms for Longevity Exercise and Weight Loss Limiting Caffeine, Alcohol, and Late-Night Unhealthy… Continue reading Potential Impact of Inadequate Sleep on Lifespan: A Closer Look at Longevity Risks
Category: Aging & Longevity
Study Suggests Optimal Age to Begin Senolytic Supplementation to Maximize Anti-Aging Benefits
Key Points: Fisetin and D+Q are known for their anti-aging effects when administered to older rodents. Because of this, and the fact that they are available without a prescription, many individuals have begun supplementing with fisetin or Q — both plant-derived flavonoids. However, studies exploring the effects of these senolytics when administered to younger rodents… Continue reading Study Suggests Optimal Age to Begin Senolytic Supplementation to Maximize Anti-Aging Benefits
Sirtuin Modulating Compounds: Influencing the Function of Key Proteins for Longevity
Contents Introduction: Explaining Sirutins Targeting Sirtuins for Different Age-Related Conditions SIRT-1 Modulators Sirt-1 Activation Synthetic Sirtuin Activators Naturally-Occurring SIRT-1 Activators Other Sirtuin modulators Choosing a Sirtuin Modulator for Use Sirtuins are a family of enzymes that depend on the molecule nicotinamide adenine dinucleotide (NAD+) for their function. In mammals, there are seven known sirtuins named… Continue reading Sirtuin Modulating Compounds: Influencing the Function of Key Proteins for Longevity
Breaking News: Harvard Study Shows Lower Oxygen Levels Drive Longer Lifespan
Key Points: Oxygen is the ubiquitous element that exists in nearly all living organisms, continuously influencing energy-producing pathways. In an effort to boost health, scientists developed a treatment known as hyperbaric oxygen therapy (HOT), designed to provide individuals with higher levels of pure oxygen. The research surrounding the health benefits of HOT is still in… Continue reading Breaking News: Harvard Study Shows Lower Oxygen Levels Drive Longer Lifespan
Study Shows Telomerase Activation in Gut Has Limited Anti-Aging Effects on Healthy Fish
Key Points In a new paper in Nature Aging called “Gut-specific telomerase expression counteracts systemic aging in telomerase-deficient zebrafish,” researchers say that “gut-specific rescue of telomerase activation leading to telomere elongation is sufficient to systemically counteract aging in zebrafish.” The key word in that sentence is “rescue,” which means that the experiments were done on… Continue reading Study Shows Telomerase Activation in Gut Has Limited Anti-Aging Effects on Healthy Fish
The Emergence of Cellular Reprogramming: True Age Reversal Technology
Contents Why Do We Age? Reversing Aging with Cellular Reprogramming How Does Cellular Reprogramming Work? Biological Clocks Partial Epigenetic Reprogramming Delivering Yamanaka Factors via Gene Therapy How Effective is Cellular Reprogramming? Reprogramming Extends Mouse Lifespan Reprogramming Reverses Aging When will Cellular Reprogramming Reach Consumers? Why Do We Age? Scientists are unable to agree upon the… Continue reading The Emergence of Cellular Reprogramming: True Age Reversal Technology
NAD⁺ Precursors: Unlocking the Fountain of Youth by Maximizing NAD+ Levels
Contents What Does NAD+ Do? Effects of Restoring NAD+ with Its Precursors NAD+ Precursor Clinical Trials NMN NR Nicotinamide Niacin Tryptophan Choosing and Obtaining NAD+ Precursors The reduction of nicotinamide adenine dinucleotide (NAD+) with age leads to declining cellular energy production and increases inflammation. These factors lead to accelerated aging and an increased incidence of… Continue reading NAD⁺ Precursors: Unlocking the Fountain of Youth by Maximizing NAD+ Levels
Senolytics: Clearing Troublesome Senescent Cells for Body Revitalization
Contents Introduction: What are senolytics? Examples of senolytics and their current data Active and Planned Senolytic Human Trials Commercially available senolytics As we grow older, the number of aged, non-proliferative senescent cells that release a milieu of inflammatory molecules to surrounding cells increases throughout our bodies. The molecule combination that senescent cells release (the senescence-associated… Continue reading Senolytics: Clearing Troublesome Senescent Cells for Body Revitalization
Scientists Successfully Increase Lifespan and Delay Brain Aging with New Prebiotic
Key Points: Our gut microbiome – an internal hub housing trillions of nutrient-boosting microorganisms, including bacteria and other microbes – is emerging as a central modulator of health and wellness. Studies have linked poor gut health to a myriad of harmful aged-related conditions like diabetes, cancer, and central nervous system complications that affect the brain.… Continue reading Scientists Successfully Increase Lifespan and Delay Brain Aging with New Prebiotic
Latest German Study: Calorie Restriction Reverses Fast and Clumsy DNA Reading During Aging
Key Points Aging affects numerous cellular processes, including the quality and concentration of proteins within cells. DNA transcription constitutes one of the essential steps in protein production from DNA sequences; however, it’s currently unknown to what extent transcription contributes to or is affected by aging. Published in Nature, Beyer and colleagues from the University of… Continue reading Latest German Study: Calorie Restriction Reverses Fast and Clumsy DNA Reading During Aging