Mitochondria are unique structures present in all cells that are essential to producing energy and stimulating growth. Malfunctional mitochondria can promote the development of degenerative brain conditions, such as Parkinson’s disease and Leigh syndrome, a dreadful neurological disorder that leads to progressive decreases in mental and movement capabilities that typically result in childhood mortalities. Unraveling… Continue reading Increasing Lifespan of Leigh Syndrome Mice with NAD⁺ Level Restoration
Category: Brain & Neurons
Manipulating NAD⁺ Levels Has Potential Therapeutic Role for Neural Damage
Traumatic brain injuries and disorders of the brain, such as Alzheimer’s disease and Parkinson’s disease, induce neuronal damage. Neuronal damage induced by injuries and diseases can become present in the short-term right after the occurrence, or it can develop chronically over time. Researchers investigate brain injuries and diseases utilizing different animal models with the ambition… Continue reading Manipulating NAD⁺ Levels Has Potential Therapeutic Role for Neural Damage
Activating Immune Cells with a Common Vitamin to Fight Off Deadly Brain Cancer
Uncontrollably growing cells can form tumors, and when tumors form, they are confronted and invaded by the body’s defense–the immune system. Yet tumors often disarm our protective immune cells, which renders them ineffective and eliminates their cancer cell killing capabilities. This is true for the deadly and highly incurable brain cancer called glioblastoma. So, finding… Continue reading Activating Immune Cells with a Common Vitamin to Fight Off Deadly Brain Cancer
NAD⁺ Precursor Improves Neuron Production and Motor Function in Mice with ALS
Amyotrophic lateral sclerosis (ALS), also called Lou Gehrig’s disease, is caused by progressive cell deterioration throughout the nervous system in motor neurons that control our muscle movements, prompting muscle weakness and eventual paralysis. Still, we don’t have effective drugs for treating ALS. The diminishing levels of a vital molecule called nicotinamide adenine dinucleotide (NAD+) is… Continue reading NAD⁺ Precursor Improves Neuron Production and Motor Function in Mice with ALS