Key Points: Fasting, usually longer than 24 hours, can potentially treat, prevent, or delay disease and enhance longevity. However, fasting for this duration can often be infeasible or dangerous for many individuals. This has prompted scientists to determine if the cellular pathways activated by fasting can be mimicked with dietary compounds. In doing so, researchers… Continue reading Supplement Combo that Mimics Fasting Counters Aging, New Study Shows
Category: Clinical Trials
FDA Greenlights Life Biosciences’ Human Study, Setting Up Pivotal Test for Aging Theory from Harvard’s David Sinclair
Key Points: One of the most renowned theories of aging attempting to explain some of the causes of aging and how to rejuvenate cells, the Information Theory of Aging from Harvard’s David Sinclair, will soon be put to the test. In that respect, Life Biosciences, a biotech company co-founded by Sinclair, received the FDA’s approval… Continue reading FDA Greenlights Life Biosciences’ Human Study, Setting Up Pivotal Test for Aging Theory from Harvard’s David Sinclair
Unpublished Results Show NMNH Triples NAD+ in First Human Trial
Key Points: As presented in a Modern Healthspan YouTube segment, longevity aficionado and host Richard Morgan shared details regarding data from the first human trial involving reduced nicotinamide mononucleotide (NMNH). According to his podcast segment, Morgan received a file from the company that sponsored the study, which contained the study’s data. Also, an alternative source,… Continue reading Unpublished Results Show NMNH Triples NAD+ in First Human Trial
A Natural Senolytic Supplement Curbs Heart Aging in New Clinical Trial
Key Points: In a recent clinical trial, Canadian scientists investigated the effect of a compound called quercetin on heart disease patients. Found in many fruits and vegetables like onions, apples, and berries, quercetin is known for its anti-oxidant and anti-inflammatory properties. With quercetin supplementation, the Canadian researchers sought to target senescent cells, one of the… Continue reading A Natural Senolytic Supplement Curbs Heart Aging in New Clinical Trial
Anti-Aging Drug Rapamycin Increases Muscle and Reduces Pain: New Results
Key Points: Modern human society and medical technology have negated many of natural selection’s effects, allowing more people to live longer. However, an epidemic of poor lifestyle choices, along with the pollutants manufactured by modern society, perpetuate chronic conditions such as lung cancer, cardiovascular disease, and dementia. Thus, while we tend to live longer, many… Continue reading Anti-Aging Drug Rapamycin Increases Muscle and Reduces Pain: New Results
Breakthrough Alzheimer’s Treatment Achieves Historic FDA Stamp of Approval
Highlights: In the realm of neurodegenerative disorders, Alzheimer’s is arguably one of the most devastating diseases, afflicting more than 6.5 million people in the U.S. alone. And although no real cure exists, the available research suggests that compounds capable of extinguishing amyloid beta plaques are promising therapeutics to mitigate this deadly disease. Accordingly, preliminary clinical… Continue reading Breakthrough Alzheimer’s Treatment Achieves Historic FDA Stamp of Approval
NR and CoQ10 Improve Kidney Function: Latest Study
Key Points About 15% of US adults have chronic kidney disease, and as many as 90% of adults with chronic kidney disease don’t know they have it. Those with severe kidney disease often suffer from declining muscle function, precipitating frailty for some. Along those lines, researchers propose that declining mitochondrial metabolism facilitates declining physical function… Continue reading NR and CoQ10 Improve Kidney Function: Latest Study
Clinical Study Shows Calorie Restriction Slows Pace of Aging in Healthy Adults
Key Points Calorie restriction, which has been shown to slow aging in animals, showed signs of slowing biological aging in the first-ever study of the effects of long-term calorie restriction on healthy, non-obese humans, shows a study published in Nature Aging. The two-year Phase 2 randomized controlled trial found that the intervention effect represented a… Continue reading Clinical Study Shows Calorie Restriction Slows Pace of Aging in Healthy Adults
New Human Study Shows NMN Substantially Increases NAD⁺ and Enhances Physical Performance
Key Points Nicotinamide mononucleotide (NMN) functions as a precursor molecule to the pro-longevity molecule nicotinamide adenine dinucleotide (NAD+). Studies using rodents have shown that NMN supplementation increases blood NAD+ levels, along with improving endurance and cardiovascular health. Whether such findings translate to humans has given mixed results from clinical trials. Some clinical studies suggest that… Continue reading New Human Study Shows NMN Substantially Increases NAD⁺ and Enhances Physical Performance
Elysium Scientists Combine NAD⁺ Booster with Sirtuin Activator to Reduce Inflammation in Liver Disease
Key Points: Approximately 1 billion people worldwide have non-alcoholic fatty liver disease (NAFLD), characterized by fat accumulation and inflammation. Rodent studies have shown that combating this rampant condition entails activating pro-longevity proteins called sirtuins. Along with sirtuin activating compounds (STACs) like pterostilbene, increasing nicotinamide adenine dinucleotide (NAD+) levels with the supplements NR or nicotinamide mononucleotide… Continue reading Elysium Scientists Combine NAD⁺ Booster with Sirtuin Activator to Reduce Inflammation in Liver Disease