Key Points Residents of Okinawa consume, on average, 11% fewer calories than others around the world, have lower body fat, and exhibit reduced mortality from age-related diseases. Although these tantalizing data show a correlation between reducing calorie intake and healthier aging, they don’t establish a causal link. Furthermore, most animal studies showing that caloric restriction… Continue reading University of Arizona Study Shows Moderate Calorie-Restricted Diet Improves Metabolism and Physical Function
Category: Metabolism
Russia Study Shows Immucillin H Enhances NR’s NAD⁺ Boosting Effect
Key Points: Our cells demand adequate NAD+ levels to fuel enzymes that modulate cell survival. As we age, our cells accumulate damage, namely to DNA, increasing the need for survival enzymes and raising the demand for NAD+. However, when these demands are unmet, cells die, organs degenerate, and disease ensues. This is why replenishing NAD+… Continue reading Russia Study Shows Immucillin H Enhances NR’s NAD⁺ Boosting Effect
Ketogenic Diet Restores Alzheimer’s Memory Deficits and Neurodegeneration, Study Shows
Key Points: Alzheimer’s mice fed a ketogenic diet have improved spatial and short-term memory. The ketogenic diet largely restores the loss of neurons, neuronal connections, and neuron degeneration in Alzheimer’s mice. The effects of the ketogenic diet are mediated by reduced brain inflammation. When challenged with inflammation over a lifetime, our organs operate with declining… Continue reading Ketogenic Diet Restores Alzheimer’s Memory Deficits and Neurodegeneration, Study Shows
Korean Study Shows Vitamin B₃ Alleviates Diabetes-Induced Eye Degeneration
Key Points: Vitamin B3 (nicotinamide) treatment reduces cell death and injury in the retinas of rats modeling diabetes. Treatment with nicotinamide enhances DNA repair in the retinas of diabetic rats. Among the myriad of risks associated with diabetes, one that severely impacts life quality is blindness, which stems from the deterioration of the retina –… Continue reading Korean Study Shows Vitamin B₃ Alleviates Diabetes-Induced Eye Degeneration
Scientists find NAD⁺ Boosting Enzyme Protects Against Diabetes and Skeletal Muscle Decline
Key Points: The Nampt activator P7C3 lowers blood glucose while increasing insulin-secreting pancreatic β cells in diabetic mice. Treatment with P7C3 increases physical endurance, as well as muscle strength and size. P7C3 raises “good” cholesterol and lowers “bad” cholesterol. As the human population rises and the elderly population expands, unprecedented numbers of individuals with age-related… Continue reading Scientists find NAD⁺ Boosting Enzyme Protects Against Diabetes and Skeletal Muscle Decline
Study Suggests Tomato Antioxidant Prevents Signs of Diabetes and Reverses Blood Vessel Aging
Key Points: Supplementing aged rats with lycopene increases the growth of blood vessels in muscle. Blood vessel growth is induced by reduced insulin resistance — a primary cause of type 2 diabetes — allowing for improved glucose (energy) utilization. Blood vessel restoration is regulated by SIRT1, a guardian protein that plays a vital role in… Continue reading Study Suggests Tomato Antioxidant Prevents Signs of Diabetes and Reverses Blood Vessel Aging
UCSD Study Shows Eating within 8-Hour Window Elevates Beneficial Gut Bacteria Molecule
Key Points: Obese mice have a dysregulated gut microbiome (bacteria and other microbes in the intestines) that is restored by eating within an 8-hour window. This time-restricted feeding improves sugar and fat metabolism, preventing weight gain. Time-restricted feeding also leads to the gut microbiome producing more GLP-1, a molecule that improves sugar metabolism. Our bodies… Continue reading UCSD Study Shows Eating within 8-Hour Window Elevates Beneficial Gut Bacteria Molecule
Study Shows NAD⁺ Precursor Prevents Diet-Induced Weight Gain in Female Mice
Key Points: NR supplementation decreases weight gain, fat mass accumulation, and elevation in cholesterol associated with obesity and aging. Supplementation with NR reduces inflammation, a hallmark of aging, in fat tissue. NR treatment also elevates metabolism and enhances physical activity levels. Nicotinamide riboside (NR) is a molecule capable of raising the declining levels of nicotinamide… Continue reading Study Shows NAD⁺ Precursor Prevents Diet-Induced Weight Gain in Female Mice
Study Shows Sesamol Prevents Weight Gain and Improves Metabolism in Middle-Aged Mice
Key Points: Sesamol treatment prevents high-fat diet-induced obesity in middle-aged mice. Treatment with sesamol prevents obesity-induced metabolic syndrome. Sesamol activates longevity-associated proteins AMPK and SIRT1. The sesame seeds on your Big Mac won’t help you lose weight, but according to a new study published in Food & Nutrition Research, sesamol — a compound present in… Continue reading Study Shows Sesamol Prevents Weight Gain and Improves Metabolism in Middle-Aged Mice
Sulforaphane — a Compound in Broccoli — Fights Off Fat
Key Points: A compound derived from broccoli called sulforaphane induces weight loss and improves blood sugar levels in obese mice. Sulforaphane prevents weight gain in lean mice fed a high-fat diet. Two billion people in the world are either obese or overweight. That’s over a quarter of the world’s population. As the rate of obesity… Continue reading Sulforaphane — a Compound in Broccoli — Fights Off Fat