Making CAR-T Cells Young Again: Restoring NAD+ to Rejuvenate Immunotherapy in Aging

Key Points: When it comes to cancer, aging has serious consequences. The risk of cancer and the likelihood that even the latest cancer treatments will fail increase with age. For younger patients, CAR-T cell therapy, which trains the immune system to recognize and attack cancer cells, has shown great promise, but not so much for… Continue reading Making CAR-T Cells Young Again: Restoring NAD+ to Rejuvenate Immunotherapy in Aging

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NAD+ Supercharges Immune System Recovery In Older Mice, Hurts Blood Stem Cells of Young Mice

Key Points: Blood stem cells help our bodies repair and grow new tissues all through our lives, and scientists have found a way to keep them from dying off too quickly as we get older. Getting rid of or blocking an enzyme that breaks down NAD+, a molecule important for keeping stem cells young, can… Continue reading NAD+ Supercharges Immune System Recovery In Older Mice, Hurts Blood Stem Cells of Young Mice

Expert Explains Role of NAD+ in Preventing Age-Related Kidney Disease  

Key Points:  According to the World Health Organization’s latest estimate, chronic kidney disease (CKD) is the ninth leading cause of death worldwide. However, despite decades of research, scientists have an incomplete understanding of the biological processes that initiate CKD. As such, there are no effective therapies that slow its progression, leading to fatal end-stage kidney… Continue reading Expert Explains Role of NAD+ in Preventing Age-Related Kidney Disease  

NAD+ & Diabetes: Harvard Study Reveals New Anti-Aging Key

Key Points Some of our cells are more important than others, particularly when it comes to losing them during aging. Like losing a piece of ourselves, the loss of some cells brings us one step closer to chronic diseases such as diabetes. Diabetes, characterized by high blood glucose levels, occurs for two primary reasons:  In… Continue reading NAD+ & Diabetes: Harvard Study Reveals New Anti-Aging Key

Most Comprehensive Study Places NAD+ at Forefront of Countering Brain Aging

Key Points:  Perhaps the most important aspect of sustaining human health is the maintenance of energy. We can’t go long without consuming energy, which comes from potatoes, chicken, and other foods. Our cells utilize food’s nutrients to produce ATP, a molecule bustling with potential energy. Moreover, they self-destruct when ATP runs too low, demonstrating the… Continue reading Most Comprehensive Study Places NAD+ at Forefront of Countering Brain Aging

Unlocking Youth: The Combined Power of NAD+ and Exercise 

Key Points:  NAD+ is a vital molecule involved in the production of our cells’ primary energy source: ATP (adenosine triphosphate). Without adequate levels of NAD+ and ATP, our cells die, making us susceptible to disease and death. Thus, maintaining our NAD+ levels, particularly with age, is critical for a long and healthy life.  Maintaining NAD+ Levels… Continue reading Unlocking Youth: The Combined Power of NAD+ and Exercise 

Anti-Aging Doctor Reveals How He Diagnoses NAD+ Deficiency

Key Points:  Dr. Darshan Shah is a Mayo Clinic-trained surgeon, now the CEO and owner of NextHealth — “The ‘Apple Store’ Of Next Generation Health.” In an interview with Dr. Oz, he discusses the importance of NAD+ (nicotinamide adenine dinucleotide) and one of its precursors NR (nicotinamide riboside). He also reveals how he knows when… Continue reading Anti-Aging Doctor Reveals How He Diagnoses NAD+ Deficiency

A New, Multifaceted Approach to Increasing Cellular NAD+ Levels

Key Points: Multiple studies have shown that taking an NAD+ precursor increases blood NAD+ levels. Yet, aside from raising NAD+, there has been a lack of human trial-based evidence that NAD+-targeting supplements work against aging, even though some rodent studies suggest that they do. Now, published in NPJ Aging, Ford and colleagues from Northumbria University… Continue reading A New, Multifaceted Approach to Increasing Cellular NAD+ Levels

What Foods Are High in NAD+?

Key Points:  From bacteria to humans, NAD+ (nicotinamide adenine dinucleotide) is essential for life. As such, not having enough NAD+ may promote organ and tissue degeneration, chronic disease, and death. For these reasons, some may wonder how to maintain sufficient NAD+ levels and if there are foods that can help with doing so.  However, when… Continue reading What Foods Are High in NAD+?