Key Points: NAD+ is a natural molecule, vital for cellular health, that declines with age in organs such as the skin, liver, and brain. According to animal studies, NAD+ decline contributes to a host of chronic conditions, including heart disease and neurodegenerative disorders like Parkinson’s disease (PD). However, NAD+ precursors like NR and NMN can… Continue reading NR Raises NAD+ Over 2-Fold More than NMN: New Study Comparing NAD+ Precursors
Category: NAD
Unpublished Results Show NMNH Triples NAD+ in First Human Trial
Key Points: As presented in a Modern Healthspan YouTube segment, longevity aficionado and host Richard Morgan shared details regarding data from the first human trial involving reduced nicotinamide mononucleotide (NMNH). According to his podcast segment, Morgan received a file from the company that sponsored the study, which contained the study’s data. Also, an alternative source,… Continue reading Unpublished Results Show NMNH Triples NAD+ in First Human Trial
New Study Shows Increasing Mitochondrial Protein Improves Energy Production and Extends Lifespan
Key Points: Aging disrupts the body’s ability to produce energy efficiently and increases chronic inflammation. As mitochondria — the cell’s energy producers — become less efficient with age, cellular energy output declines while harmful byproducts known as reactive oxygen species accumulate beyond the cell’s ability to neutralize them. These byproducts damage cells and accelerate aging. Over… Continue reading New Study Shows Increasing Mitochondrial Protein Improves Energy Production and Extends Lifespan
The Latest Insight on Anti-Aging Therapeutics Targeting Cardiovascular Disease
Key Points: As the global population shifts towards an aged populace, a phenomenon referred to as the “silver tsunami,” so do the medical and socioeconomic burdens of heart disease. As such, as published in Cardiovascular Research, Kroemer and colleagues from Sorbonne University in France propose that aging is one of, if not the, critical risk… Continue reading The Latest Insight on Anti-Aging Therapeutics Targeting Cardiovascular Disease
NAD+ and Aging: What the Latest Research Says
Key Points: In today’s media landscape, it can be difficult to trust influencers, even when they are scientists. Within the health and longevity space, many are guilty of overhyping scientific results to make the supplement they are pushing more alluring. These scientific results are often from animal studies, which do not always translate to humans. … Continue reading NAD+ and Aging: What the Latest Research Says
A Harvard-Trained Doctor’s Top 5 Anti-Aging Supplements
Key Points: Dr. Josh Helman is a Harvard-trained physician who primarily focuses on reversing and preventing Alzheimer’s disease. Through his research on this age-related neurodegenerative disorder, he has become an expert of sorts on aging intervention supplements. As such, in a NewsBreak press release, Dr. Helman shared his top five supplements to counteract the effects… Continue reading A Harvard-Trained Doctor’s Top 5 Anti-Aging Supplements
Top Aging Expert & Peter Attia Discuss NAD+ Precursors: Taking NMN and NR Together
Key Points: In episode #359 of The Peter Attia Drive podcast, Dr. Peter Attia has a conversation with Dr. Eric Verdin, the CEO and President of the Buck Institute for Research on Aging. They discuss several topics, including the role of NAD+ in aging, which will be the focus of this article. Beginning their discussion… Continue reading Top Aging Expert & Peter Attia Discuss NAD+ Precursors: Taking NMN and NR Together
Making CAR-T Cells Young Again: Restoring NAD+ to Rejuvenate Immunotherapy in Aging
Key Points: When it comes to cancer, aging has serious consequences. The risk of cancer and the likelihood that even the latest cancer treatments will fail increase with age. For younger patients, CAR-T cell therapy, which trains the immune system to recognize and attack cancer cells, has shown great promise, but not so much for… Continue reading Making CAR-T Cells Young Again: Restoring NAD+ to Rejuvenate Immunotherapy in Aging
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NAD+ Supercharges Immune System Recovery In Older Mice, Hurts Blood Stem Cells of Young Mice
Key Points: Blood stem cells help our bodies repair and grow new tissues all through our lives, and scientists have found a way to keep them from dying off too quickly as we get older. Getting rid of or blocking an enzyme that breaks down NAD+, a molecule important for keeping stem cells young, can… Continue reading NAD+ Supercharges Immune System Recovery In Older Mice, Hurts Blood Stem Cells of Young Mice