Key Points: From bacteria to humans, NAD+ (nicotinamide adenine dinucleotide) is essential for life. As such, not having enough NAD+ may promote organ and tissue degeneration, chronic disease, and death. For these reasons, some may wonder how to maintain sufficient NAD+ levels and if there are foods that can help with doing so. However, when… Continue reading What Foods Are High in NAD+?
Category: NAD
Whole-Brain NAD+ Levels Decline with Age, New Study Shows
Key Points: With vital roles in brain aging, cognitive function, and neurodegeneration, NAD+ (nicotinamide adenine dinucleotide) has instigated a flurry of intensive scientific investigation. On the premise that brain NAD+ levels decline with age, NAD+ replenishing therapies could counteract the cellular dysfunction underlying the brain’s time-dependent structural and functional deterioration. However, non-invasively quantifying NAD+ levels… Continue reading Whole-Brain NAD+ Levels Decline with Age, New Study Shows
NAD+ Precursors, Aging, and Longevity: Dr. Peter Attia’s Thoughts
Key Points: Nicotinamide adenine dinucleotide (NAD+) is a fundamental coenzyme present in every living cell, crucial for protecting our genetic blueprints (DNA), enhancing energy production, and boosting metabolism. Without NAD+, human life would cease to exist. Over the last decade, NAD+ has become a focal point of aging and longevity research, but the lack of… Continue reading NAD+ Precursors, Aging, and Longevity: Dr. Peter Attia’s Thoughts
Is NAD+ the Same as Vitamin B3?
Key Points: There are three naturally occurring forms of vitamin B3: In the early 1900s, an epidemic of pellagra spread across the American South, afflicting mostly malnourished farmers. The disease triggered madness and mortality rates as high as 64% within insane asylums. The culprit was vitamin B3 deficiency, leading to the creation of vitamin B3… Continue reading Is NAD+ the Same as Vitamin B3?
Are There Hidden Dangers to Taking NAD+ Supplements?
Key Points: Boosting NAD+ can revitalize the NAD+ levels of particular individuals, including obese and older adults. Furthermore, restoring NAD+ can bring about an assortment of benefits connected to slowing aging. But are there any downsides? The following are the potential dangers associated with NAD+ and the NAD+ precursors niacin, nicotinamide, NR (nicotinamide riboside), and… Continue reading Are There Hidden Dangers to Taking NAD+ Supplements?
The Top 10 Potential Benefits of NAD+ Supplements
The top 10 benefits (with one bonus) involve: NAD+ stands for nicotinamide adenine dinucleotide, a fundamental molecule that plays many roles in keeping our cells healthy and alive. However, under certain circumstances, our natural NAD+ levels decline. As such, supplementing with NAD+ can potentially have restorative benefits. Don’t Be Fooled by False Claims Many clinics… Continue reading The Top 10 Potential Benefits of NAD+ Supplements
A New NAD+ Precursor More Stable than NMN and NR: Trigonelline
Key Points: After spending an entire day in a test tube of human blood that has had the blood cells removed (serum), the bonds that hold together NR and NMN fall apart, as shown by Dr. Sorrentino in a short talk given at the 2023 Aging Research & Drug Discovery Meeting. In contrast, trigonelline remains… Continue reading A New NAD+ Precursor More Stable than NMN and NR: Trigonelline
Anti-Aging Scientist Insists NR Is the Superior NAD+ Precursor, Is There Any Truth to His Claims?
Key Points: Charles Brenner, Ph.D. is a biochemist who studies NAD+ metabolism and the NAD+ precursor nicotinamide riboside (NR). He is Chief Scientific Advisor to ChromaDex, a company that sells NR through the brand TRU NIAGEN. On September 4th, Brenner participated in an “ask me anything” (AMA) on Reddit, where members of the forum asked… Continue reading Anti-Aging Scientist Insists NR Is the Superior NAD+ Precursor, Is There Any Truth to His Claims?
NAD⁺ Precursor NR Reduces Side Effects of Anticancer Radiation Therapy: New Study
Key Points: Radiotherapy involving the treatment of cancer patients with ionizing radiation against tumors comes with a troublesome risk — it contributes to accelerated aging. A faster pace of aging leads to chronic health conditions in 73.4% of childhood cancer survivors. Surprisingly, no countermeasures against radiation-induced premature aging have been developed. Published in Aging Cell,… Continue reading NAD⁺ Precursor NR Reduces Side Effects of Anticancer Radiation Therapy: New Study
Harvard’s David Sinclair: NAD⁺ Precursor NMN Increases Lifespan in Unpublished Study
Key Points: David Sinclair’s research at Harvard Medical School focuses on finding ways to slow the aging process. Currently, there exist a select few anti-aging agents that are capable of doing so, and nicotinamide mononucleotide (NMN) may now be one of them. On June 23, 2023, Sinclair appeared on the World of DaaS podcast with… Continue reading Harvard’s David Sinclair: NAD⁺ Precursor NMN Increases Lifespan in Unpublished Study