Key Points: Scientists have begun to identify the underlying processes that drive aging, for which DNA damage is primary. Therapeutically targeting these underlying processes, especially primary drivers of aging like DNA damage, could counter the aging process and prevent or delay age-related diseases like cancer, neurodegenerative diseases, and diabetes. Now, as reported in Heliyon, researchers… Continue reading NAD⁺ Booster NR Counters Aging by Alleviating Cellular Stress, Danish Study Shows
Category: NAD
Cocktail of Nutraceuticals with NAD⁺ Booster Effectively Protects Against Liver Injury: New Brazilian Study
Key Points Nutraceuticals like nicotinamide adenine dinucleotide (NAD+)-boosting niacin have been shown to alleviate and prevent aging-associated health conditions like metabolic disorders and cardiovascular disease. Recently, researchers have begun focusing on their synergistic benefits when consumed in combination. Published in the International Journal of Molecular Sciences, Galvao and colleagues from the University of Sao Paulo… Continue reading Cocktail of Nutraceuticals with NAD⁺ Booster Effectively Protects Against Liver Injury: New Brazilian Study
Is NAD⁺ Joe Rogan’s Secret to Long-Form Conversation?
Key Points: Joe Rogan is a comedian and UFC commentator best known for his podcast the Joe Rogan Experience on Spotify. Astonishingly, Rogan and his guests hold the attention of an estimated 11 million listeners per episode. Even more perplexing in an online world of 15-second videos is that each podcast last an average of… Continue reading Is NAD⁺ Joe Rogan’s Secret to Long-Form Conversation?
NAD⁺ Precursors: Unlocking the Fountain of Youth by Maximizing NAD+ Levels
Contents What Does NAD+ Do? Effects of Restoring NAD+ with Its Precursors NAD+ Precursor Clinical Trials NMN NR Nicotinamide Niacin Tryptophan Choosing and Obtaining NAD+ Precursors The reduction of nicotinamide adenine dinucleotide (NAD+) with age leads to declining cellular energy production and increases inflammation. These factors lead to accelerated aging and an increased incidence of… Continue reading NAD⁺ Precursors: Unlocking the Fountain of Youth by Maximizing NAD+ Levels
Researchers Demonstrate NAD+ Can Help with Stroke Recovery
Key Points: The majority of strokes are caused when the blood vessels supplying the brain become blocked, leading to ischemia, or oxygen deprivation, in the brain tissue. The subsequent injuries following stroke – due to the brain being deprived of oxygen – can require vast amounts of extra care and therapies, decreasing patients’ quality of… Continue reading Researchers Demonstrate NAD+ Can Help with Stroke Recovery
NAD+ Deficiency in Arthritis Patients Reversed by NMN and NR: Latest Study Findings
Key Points Rheumatoid arthritis, an inflammatory disease where one’s own immune system degrades joints and tendons, affects about 1% to 2% of the US population. Although researchers have linked inflammation to the disease, little is known about underlying factors contributing to it. Moreover, declining NAD+ levels have been tied to numerous age-related diseases, but whether… Continue reading NAD+ Deficiency in Arthritis Patients Reversed by NMN and NR: Latest Study Findings
NAD+ Decline Identified as a Therapeutic Target for Kidney Injury
Key Points: Researchers from Beijing demonstrated that a leading cause of kidney injury in pediatric patients is tied to the dysregulation of NAD+. In pediatric patients with obstructive nephropathy, the enzyme CD38, which drains NAD+ supplies, was highly upregulated, and when the researchers blocked CD38 or supplement NAD+ in mice with obstructed kidneys, they observed… Continue reading NAD+ Decline Identified as a Therapeutic Target for Kidney Injury
NIA Researchers Show NR Halts Age-Related Hearing Loss
Key Points: Our senses allow us to formulate our perceptions of the world, with each sense adding a unique layer to the bigger picture. Unfortunately, our sense of hearing gets hit the hardest as we age, increasing the risk of age-related cognitive decline and dementia. Although treatments for age-related hearing loss (ARHL) are extremely limited,… Continue reading NIA Researchers Show NR Halts Age-Related Hearing Loss
Scientists find NAD⁺ Boosting Enzyme Protects Against Diabetes and Skeletal Muscle Decline
Key Points: The Nampt activator P7C3 lowers blood glucose while increasing insulin-secreting pancreatic β cells in diabetic mice. Treatment with P7C3 increases physical endurance, as well as muscle strength and size. P7C3 raises “good” cholesterol and lowers “bad” cholesterol. As the human population rises and the elderly population expands, unprecedented numbers of individuals with age-related… Continue reading Scientists find NAD⁺ Boosting Enzyme Protects Against Diabetes and Skeletal Muscle Decline
New Study Shows NAD⁺ Nanoparticles Increase Survival from Sepsis by Over Fourfold in Mice
Key Points: Treating septic mice with lipid nanoparticles (NPs) loaded with nicotinamide adenine dinucleotide (NAD+) increases their survival rate from 21% to 93%. Treatment with loaded NPs stops immune cells from dying, blocking the immunosuppressive response caused by sepsis. The primary cell energy currency (ATP) is restored in multiple organs of septic mice following treatment… Continue reading New Study Shows NAD⁺ Nanoparticles Increase Survival from Sepsis by Over Fourfold in Mice