Key Points: Cardiovascular disease (CVD) is responsible for the most deaths worldwide and is associated with age-related NAD+ depletion. Therefore, NAD+ boosters like NMN could counter CVD by replenishing lost NAD+. Now, Nakajo and colleagues from the DHC Corporation in Japan report in Toxicology in Vitro that NMN inhibits oxidative stress-induced damage. Namely, in response… Continue reading Japanese Study Shows NAD⁺ Precursor NMN Reduces Senescence to Boost Cardiovascular Health
Category: NAD
Who Should Not Take An NAD⁺ Supplement?
Key Points: In recent years, NAD+ has seen a rise in popularity with scientists like Dr. David Sinclair touting its anti-aging benefits. Contributing to this popularity is a rise in scientific research revealing the underlying causes of aging, which includes a decline in NAD+. What is NAD+? Nicotinamide adenine dinucleotide (NAD+) is a naturally occurring… Continue reading Who Should Not Take An NAD⁺ Supplement?
New NAD⁺ Blood Test Kit Available
Key Points Declining NAD+ levels with age in human blood, muscle, and saliva has been linked to aging and age-related conditions like frailty, arthritis, and heart failure. To avoid ailments associated with falling NAD+ levels during aging, researchers have proposed replenishing NAD+ with precursors like NMN. Conventional techniques that measure how NMN affects NAD+ levels… Continue reading New NAD⁺ Blood Test Kit Available
NAD⁺ Booster NR Counters Aging by Alleviating Cellular Stress, Danish Study Shows
Key Points: Scientists have begun to identify the underlying processes that drive aging, for which DNA damage is primary. Therapeutically targeting these underlying processes, especially primary drivers of aging like DNA damage, could counter the aging process and prevent or delay age-related diseases like cancer, neurodegenerative diseases, and diabetes. Now, as reported in Heliyon, researchers… Continue reading NAD⁺ Booster NR Counters Aging by Alleviating Cellular Stress, Danish Study Shows
Cocktail of Nutraceuticals with NAD⁺ Booster Effectively Protects Against Liver Injury: New Brazilian Study
Key Points Nutraceuticals like nicotinamide adenine dinucleotide (NAD+)-boosting niacin have been shown to alleviate and prevent aging-associated health conditions like metabolic disorders and cardiovascular disease. Recently, researchers have begun focusing on their synergistic benefits when consumed in combination. Published in the International Journal of Molecular Sciences, Galvao and colleagues from the University of Sao Paulo… Continue reading Cocktail of Nutraceuticals with NAD⁺ Booster Effectively Protects Against Liver Injury: New Brazilian Study
Is NAD⁺ Joe Rogan’s Secret to Long-Form Conversation?
Key Points: Joe Rogan is a comedian and UFC commentator best known for his podcast the Joe Rogan Experience on Spotify. Astonishingly, Rogan and his guests hold the attention of an estimated 11 million listeners per episode. Even more perplexing in an online world of 15-second videos is that each podcast last an average of… Continue reading Is NAD⁺ Joe Rogan’s Secret to Long-Form Conversation?
NAD⁺ Precursors: Unlocking the Fountain of Youth by Maximizing NAD+ Levels
Contents What Does NAD+ Do? Effects of Restoring NAD+ with Its Precursors NAD+ Precursor Clinical Trials NMN NR Nicotinamide Niacin Tryptophan Choosing and Obtaining NAD+ Precursors The reduction of nicotinamide adenine dinucleotide (NAD+) with age leads to declining cellular energy production and increases inflammation. These factors lead to accelerated aging and an increased incidence of… Continue reading NAD⁺ Precursors: Unlocking the Fountain of Youth by Maximizing NAD+ Levels
Researchers Demonstrate NAD+ Can Help with Stroke Recovery
Key Points: The majority of strokes are caused when the blood vessels supplying the brain become blocked, leading to ischemia, or oxygen deprivation, in the brain tissue. The subsequent injuries following stroke – due to the brain being deprived of oxygen – can require vast amounts of extra care and therapies, decreasing patients’ quality of… Continue reading Researchers Demonstrate NAD+ Can Help with Stroke Recovery
NAD+ Deficiency in Arthritis Patients Reversed by NMN and NR: Latest Study Findings
Key Points Rheumatoid arthritis, an inflammatory disease where one’s own immune system degrades joints and tendons, affects about 1% to 2% of the US population. Although researchers have linked inflammation to the disease, little is known about underlying factors contributing to it. Moreover, declining NAD+ levels have been tied to numerous age-related diseases, but whether… Continue reading NAD+ Deficiency in Arthritis Patients Reversed by NMN and NR: Latest Study Findings
NAD+ Decline Identified as a Therapeutic Target for Kidney Injury
Key Points: Researchers from Beijing demonstrated that a leading cause of kidney injury in pediatric patients is tied to the dysregulation of NAD+. In pediatric patients with obstructive nephropathy, the enzyme CD38, which drains NAD+ supplies, was highly upregulated, and when the researchers blocked CD38 or supplement NAD+ in mice with obstructed kidneys, they observed… Continue reading NAD+ Decline Identified as a Therapeutic Target for Kidney Injury