Key Points: Metformin has been used for decades to treat diabetes; however, many researchers have recently found that metformin has numerous anti-aging capabilities. A new study shows that metformin can be used to prevent another aging concern, the degradation of tendons – the connective tissue attaching muscles to bones. The study, from the University of… Continue reading Study Shows Metformin Prevents Connective Tissue Aging
Category: Skin & Muscle
New Study Shows Rejuvenated Stem Cells Prolong Lifespan and Increase Muscle Fitness
Key Points: Aging inevitably compromises the regenerative potential of stem cells, leading to impaired tissue healing and muscle atrophy. Thus, identifying treatments that rejuvenate aged stem cells is vital to thwarting age-related conditions linked to poor stem cell function. Researchers have pinpointed a cell-cycle protein called Cdc42, the activity of which increases with aging and… Continue reading New Study Shows Rejuvenated Stem Cells Prolong Lifespan and Increase Muscle Fitness
Young to Old Gut Bacteria Transfer Rejuvenates Muscle and Skin in Latest Study
Key Points: Some have likened our gut bacteria — the bacteria that live in our gut — to an organ. This “organ” is capable of modulating our immune system and metabolism, as well as other organs like the brain and muscle. However, our gut bacteria change with aging and may contribute to age-related diseases. This… Continue reading Young to Old Gut Bacteria Transfer Rejuvenates Muscle and Skin in Latest Study
Senolytic Agent Rejuvenates Aged Human Skin: Japanese Study
Key Points As we grow older, our skin loses its vibrant appearance and begins to wrinkle. Age-associated wrinkles arise primarily from the loss of structural proteins called collagens. Recent research in rodents suggests senolytics – compounds that selectively eliminate senescent cells – reduce the abundance of the collagen-degrading inflammatory SASP and improve the function of… Continue reading Senolytic Agent Rejuvenates Aged Human Skin: Japanese Study
New Study Shows Particles Secreted from Stem Cells Significantly Reduce Aging
Key Points: Stem cells have continuously been touted as a promising aging intervention, as they hold self-renewal and anti-inflammatory properties that contribute to organ rejuvenation and immune system regulation. However, stem cell therapy requires some refinement before it can be widely used. Recently, scientists have honed in on small fat packets secreted from stem cells… Continue reading New Study Shows Particles Secreted from Stem Cells Significantly Reduce Aging
Scientists find NAD⁺ Boosting Enzyme Protects Against Diabetes and Skeletal Muscle Decline
Key Points: The Nampt activator P7C3 lowers blood glucose while increasing insulin-secreting pancreatic β cells in diabetic mice. Treatment with P7C3 increases physical endurance, as well as muscle strength and size. P7C3 raises “good” cholesterol and lowers “bad” cholesterol. As the human population rises and the elderly population expands, unprecedented numbers of individuals with age-related… Continue reading Scientists find NAD⁺ Boosting Enzyme Protects Against Diabetes and Skeletal Muscle Decline
Japan Study Shows Pearl Extract Rejuvenates Aged Brain and Skin
Key Points: Treatment with pearl extract improves memory deficits in aged mice by preventing neurodegeneration. Pearl extract rejuvenates the fur of aged mice while reversing aspects of skin aging, such as thinning and wrinkles. Rejuvenation is attributed to elevated antioxidants and reduced cellular stress. Pearls are often associated with a vintage look and grandmotherly vibe.… Continue reading Japan Study Shows Pearl Extract Rejuvenates Aged Brain and Skin
Researchers in China Reverse Skin Aging with Stem Cell Therapy
Key Points: Stem cell treatment removes wrinkles, smooths skin, increases skin thickness, and enhances collagen production in mice with aged-skin. Treatment with stem cells improves wound healing in human skin tissue by limiting the accumulation of senescent cells – growth-arrested cells linked to aging. The beneficial effects of stem cell therapy are mediated by alleviating oxidative… Continue reading Researchers in China Reverse Skin Aging with Stem Cell Therapy
New Longevity Molecule Found to Prolong Lifespan and Delay Cardiac and Muscle Aging
Key Points: Our genetic blueprints (DNA) are constantly being studied to identify longevity-linked genes and pathways that may hold the key to prolonging our lifespan. One particular gene that has strong ties to longevity is Cisd2. In addition to extending the lifespan of rodents through increased activity, activation of Cisd2 protects against cardiac dysfunction and… Continue reading New Longevity Molecule Found to Prolong Lifespan and Delay Cardiac and Muscle Aging
Latest Mayo Clinic Study Shows Senolytic Combo Counters Age-Related Muscle Weakness
Key Points: D + Q lowers senescent cell (aged cell) burden and increases grip strength in older mice. Senescent cells are elevated in older individuals and associated with reduced muscle strength. For older individuals, muscle weakness can make it difficult to get up from a chair, or even walk, let alone catch oneself in a… Continue reading Latest Mayo Clinic Study Shows Senolytic Combo Counters Age-Related Muscle Weakness