Key Points: The anti-aging molecule klotho has gained the attention of researchers exploring the limits of gene therapy — a technique that modifies a person’s genes — and delaying cellular aging. To do so, Roig-Soriano and colleagues injected the klotho gene into mice. They injected mice that were 6 months old, roughly equivalent to a 31-year-old human,… Continue reading One-Time Anti-Aging Gene Therapy Treatment Prolongs Life by 20%, New Study Shows
Category: Aging & Longevity
Common Diabetes Medication Might Extend Life, Suggests New Study
Key Points: Dysfunction of the cell’s powerhouse—mitochondria—is a hallmark of aging and has been tied to age-related neurodegenerative disorders, cardiovascular disease, and metabolic conditions. Interestingly, the diabetes drug chlorpropamide has been shown to exert effects against aging in worms by altering mitochondrial function. This finding has drawn attention to the class of diabetes medications to… Continue reading Common Diabetes Medication Might Extend Life, Suggests New Study
Expert Panel Agrees On Biomarkers of Aging for Testing Therapeutics
Key Points: Published in the Journals of Gerontology, 60 aging research experts from various international institutions, including the University of Pennsylvania and the Germany-based Max Planck Insitute for Biology and Ageing, arrived at a consensus to designate markers of aging—referred to as biomarkers. These aging markers included some related to physiological function, inflammation, physical function,… Continue reading Expert Panel Agrees On Biomarkers of Aging for Testing Therapeutics
Longevity Compound Thwarts Age-Related Joint Degeneration: New Study Reveals
Key Points: Aging is a relentless biological process that affects every tissue in the body, and our joints are no exception. Osteoarthritis (OA), a degenerative joint disorder, affects millions worldwide and is exacerbated by both aging and surgical trauma. While traditional treatments focus on managing pain and inflammation, emerging research suggests that metabolic interventions may… Continue reading Longevity Compound Thwarts Age-Related Joint Degeneration: New Study Reveals
Harvard Study Reveals that Omega-3s, Vitamin D, and Exercise Additively Slow Biological Aging
Key Points: There’s a reason why you keep hearing about omega-3s, the healthy fats found in fish, such as salmon and sardines. Omega-3 supplements are everywhere, always on the shelves of grocery and vitamin stores. Why? Because you basically need them for your brain to function optimally, both cognitively and emotionally. Not to mention that… Continue reading Harvard Study Reveals that Omega-3s, Vitamin D, and Exercise Additively Slow Biological Aging
New Age-Reversal Therapy Prolongs Life by Targeting Senescent Cells
Key Points: Mayo Clinic’s conceptual framework for treating the most deadly age-related diseases, including cancer and cardiovascular disease, involves targeting a single shared biological factor — senescent cells. Until now, the most well-established way of reducing senescent cells has been senolytics — compounds that selectively eliminate senescent cells. However, challenging the dogma that senescent cells are… Continue reading New Age-Reversal Therapy Prolongs Life by Targeting Senescent Cells
Combining Senolytics with Blood Pressure Medication Counteracts Gut Aging and Promotes Longevity, Suggests New Study
Key Points: Published in Nature Aging, Zhao and colleagues from Fudan University in China show that a metabolite, PAGln, from gut bacteria accumulates with age in the blood of humans. Interestingly, injecting young mice with PAGln increases the abundance of proteins associated with senescent cells, providing evidence that the metabolite increases levels of senescent cells… Continue reading Combining Senolytics with Blood Pressure Medication Counteracts Gut Aging and Promotes Longevity, Suggests New Study
ChatGPT and Retro Biosciences: The Future of AI-Backed Age-Reversal Technology?
Key Points: OpenAI’s CEO Sam Altman made headlines nearly two years ago after revealing his $180 million investment in Retro Biosciences, a biotechnology company in Northern California focused on human longevity (living longer). Now OpenAI and Retro Biosciences are joining forces to tackle what some have called true age-reversal technology — cellular reprogramming. What is… Continue reading ChatGPT and Retro Biosciences: The Future of AI-Backed Age-Reversal Technology?
Would You Pay $6,000 to Know What Might Kill You?
Key Points: If you had the chance to learn what might one day end your life, how much would you pay for that knowledge? Well, it turns out that $6,000 could be the answer, according to the healthcare AI startup Ezra. On October 22, 2024, Ezra announced the launch of “the world’s most advanced longevity… Continue reading Would You Pay $6,000 to Know What Might Kill You?
New Study Shows Stem Cells Stop Aging and Prolong Life
Key Points: Researchers from Boston Children’s Hospital and Harvard Medical School have found that transplanting a subset of “young” stem cells from old mice into middle-aged mice increases the lifespan of middle-aged mice by over 9%. Furthermore, the “young” stem cells delayed multiple manifestations of aging by rejuvenating the immune system and improving physical performance,… Continue reading New Study Shows Stem Cells Stop Aging and Prolong Life