Key Points: There’s a reason why you keep hearing about omega-3s, the healthy fats found in fish, such as salmon and sardines. Omega-3 supplements are everywhere, always on the shelves of grocery and vitamin stores. Why? Because you basically need them for your brain to function optimally, both cognitively and emotionally. Not to mention that… Continue reading Harvard Study Reveals that Omega-3s, Vitamin D, and Exercise Additively Slow Biological Aging
Category: Aging & Longevity
New Age-Reversal Therapy Prolongs Life by Targeting Senescent Cells
Key Points: Mayo Clinic’s conceptual framework for treating the most deadly age-related diseases, including cancer and cardiovascular disease, involves targeting a single shared biological factor — senescent cells. Until now, the most well-established way of reducing senescent cells has been senolytics — compounds that selectively eliminate senescent cells. However, challenging the dogma that senescent cells are… Continue reading New Age-Reversal Therapy Prolongs Life by Targeting Senescent Cells
Combining Senolytics with Blood Pressure Medication Counteracts Gut Aging and Promotes Longevity, Suggests New Study
Key Points: Published in Nature Aging, Zhao and colleagues from Fudan University in China show that a metabolite, PAGln, from gut bacteria accumulates with age in the blood of humans. Interestingly, injecting young mice with PAGln increases the abundance of proteins associated with senescent cells, providing evidence that the metabolite increases levels of senescent cells… Continue reading Combining Senolytics with Blood Pressure Medication Counteracts Gut Aging and Promotes Longevity, Suggests New Study
ChatGPT and Retro Biosciences: The Future of AI-Backed Age-Reversal Technology?
Key Points: OpenAI’s CEO Sam Altman made headlines nearly two years ago after revealing his $180 million investment in Retro Biosciences, a biotechnology company in Northern California focused on human longevity (living longer). Now OpenAI and Retro Biosciences are joining forces to tackle what some have called true age-reversal technology — cellular reprogramming. What is… Continue reading ChatGPT and Retro Biosciences: The Future of AI-Backed Age-Reversal Technology?
Would You Pay $6,000 to Know What Might Kill You?
Key Points: If you had the chance to learn what might one day end your life, how much would you pay for that knowledge? Well, it turns out that $6,000 could be the answer, according to the healthcare AI startup Ezra. On October 22, 2024, Ezra announced the launch of “the world’s most advanced longevity… Continue reading Would You Pay $6,000 to Know What Might Kill You?
New Study Shows Stem Cells Stop Aging and Prolong Life
Key Points: Researchers from Boston Children’s Hospital and Harvard Medical School have found that transplanting a subset of “young” stem cells from old mice into middle-aged mice increases the lifespan of middle-aged mice by over 9%. Furthermore, the “young” stem cells delayed multiple manifestations of aging by rejuvenating the immune system and improving physical performance,… Continue reading New Study Shows Stem Cells Stop Aging and Prolong Life
Cumulative Research Suggests Coffee Prolongs Life by 1.8 Years
Key Points: Published in Ageing Research Reviews, Cunha and Lopes from the University of Coimbra in Portugal review studies showing an association between regular coffee intake and an average of 1.8 years of extended lifespan. The researchers also provide an overview of data suggesting that drinking coffee reduces the risk of age-related diseases like diabetes,… Continue reading Cumulative Research Suggests Coffee Prolongs Life by 1.8 Years
Biotech Startup Aims to Harness New NAD+-Related Drug Against Aging
Key Points: A new longevity therapeutics-focused biotech company called MetaShape Pharma, based in Basel, Switzerland, is developing new therapeutics targeting NAD+ to fight age-related diseases. The company’s approach encompasses the inhibition of an enzyme—PNP— that limits cells’ capacity to synthesize NAD+. To start their NAD+-related pharmaceutical venture, the company will target well-defined age-related conditions like… Continue reading Biotech Startup Aims to Harness New NAD+-Related Drug Against Aging
Newly Proposed Aging Mechanism: Digestive Enzymes May Be Eating Us from Within
Key Points: Published in PLoS ONE, Schmid-Schönbein and colleagues from the University of California, San Diego show that digestive enzymes leaked from the gut contribute to organ tissue structural protein (collagen) degradation in old rats. These digestive enzymes, such as trypsin and amylase, also break down insulin receptors in the brain—and possibly other organs—leading to… Continue reading Newly Proposed Aging Mechanism: Digestive Enzymes May Be Eating Us from Within
The Most Shredded 55-Year-Old Bill Maeda’s Longevity Secrets — Including Supplementing with NAD+
Key Points: At 55, Bill Maeda has obtained a seemingly unattainable physique, and in an interview with Thomas DeLauer, he makes it clear that there’s no one-size-fits-all approach to health and longevity. The following is a closer look at how Bill maintains a low body fat percentage while living an intuitive, flexible lifestyle. Diet Bill’s… Continue reading The Most Shredded 55-Year-Old Bill Maeda’s Longevity Secrets — Including Supplementing with NAD+