Key Points: Published in Ageing Research Reviews, Cunha and Lopes from the University of Coimbra in Portugal review studies showing an association between regular coffee intake and an average of 1.8 years of extended lifespan. The researchers also provide an overview of data suggesting that drinking coffee reduces the risk of age-related diseases like diabetes,… Continue reading Cumulative Research Suggests Coffee Prolongs Life by 1.8 Years
Category: Aging & Longevity
Biotech Startup Aims to Harness New NAD+-Related Drug Against Aging
Key Points: A new longevity therapeutics-focused biotech company called MetaShape Pharma, based in Basel, Switzerland, is developing new therapeutics targeting NAD+ to fight age-related diseases. The company’s approach encompasses the inhibition of an enzyme—PNP— that limits cells’ capacity to synthesize NAD+. To start their NAD+-related pharmaceutical venture, the company will target well-defined age-related conditions like… Continue reading Biotech Startup Aims to Harness New NAD+-Related Drug Against Aging
Newly Proposed Aging Mechanism: Digestive Enzymes May Be Eating Us from Within
Key Points: Published in PLoS ONE, Schmid-Schönbein and colleagues from the University of California, San Diego show that digestive enzymes leaked from the gut contribute to organ tissue structural protein (collagen) degradation in old rats. These digestive enzymes, such as trypsin and amylase, also break down insulin receptors in the brain—and possibly other organs—leading to… Continue reading Newly Proposed Aging Mechanism: Digestive Enzymes May Be Eating Us from Within
The Most Shredded 55-Year-Old Bill Maeda’s Longevity Secrets — Including Supplementing with NAD+
Key Points: At 55, Bill Maeda has obtained a seemingly unattainable physique, and in an interview with Thomas DeLauer, he makes it clear that there’s no one-size-fits-all approach to health and longevity. The following is a closer look at how Bill maintains a low body fat percentage while living an intuitive, flexible lifestyle. Diet Bill’s… Continue reading The Most Shredded 55-Year-Old Bill Maeda’s Longevity Secrets — Including Supplementing with NAD+
Are We Supposed to Live Past 40?
Key Points: As modern global civilization emerged, the average human lifespan was half what it is today. For this reason, some have pondered the purpose of life after reaching 40. This intriguing question can be explored from various angles, including biological, historical, and societal perspectives. To understand, we must delve into life expectancy data, evolutionary… Continue reading Are We Supposed to Live Past 40?
Approved Drugs that Increase the Chances of Living a Longer Life
Key Points: In the arenas of longevity (living longer) and healthspan (living healthier longer) repurposing government-approved drugs strikes the fancy. The problem is that approved drugs are usually prescribed to individuals with unhealthy conditions. For this reason, Swiss researchers say they sought to determine which approved drugs could lower the risk of early mortality in the general… Continue reading Approved Drugs that Increase the Chances of Living a Longer Life
Bruce Ames’ Triage Theory & The Eleven Longevity Vitamins
Key Points: The triage theory states that in response to moderate nutrient deficiencies, enzymes necessary for longevity shut off in favor of enzymes necessary for survival and reproduction. That is, sufficient intake of the known 30 vitamins and minerals will lead to a longer life. However, deficiencies will lead to an insidious accumulation of clinically… Continue reading Bruce Ames’ Triage Theory & The Eleven Longevity Vitamins
Nano-Sized Vesicle Infusions Break Rat Lifespan Record
Key Points: Blood plasma from young mice has been shown to alleviate signs of aging and extend lifespan in older mice, making way for some human zealots attempting to prolong their lives by trying blood transfusions from younger donors. All the same, the exact way that young blood rejuvenates tissues and prolongs life in these… Continue reading Nano-Sized Vesicle Infusions Break Rat Lifespan Record
Is Hyperbaric Oxygen Therapy A Rip-off?
Key Points: One of the latest anti-aging and life-extension trends is hyperbaric oxygen therapy (HBOT). Celebrities like Justin Bieber, Michael Phelps, Steve Aoki, and Miyam Bialik—who not only stars on The Big Bang Theory but also has a PhD in neuroscience—all swear by HBOT. Physician-backed longevity clinics offering medical-grade HBOT promise to “reverse the biology… Continue reading Is Hyperbaric Oxygen Therapy A Rip-off?
Will Interventions that Delay Aging in Animals Work for Humans?
Key Points: The identification of the hallmarks of aging—characteristics of age-associated physiological decline that therapeutics can target to slow or reverse aging—has served as a crucial step in developing aging intervention technologies. Reported in Trends in Endocrinology and Metabolism, Liu and colleagues from Shenzhen University Medical School in China relay data showing that some interventions… Continue reading Will Interventions that Delay Aging in Animals Work for Humans?